






Revolutionary Formula
FIRST on the market that incorporated Ca-AKG and Resveratrol with NAD+ for maximum anti-aging:
50% NRHM: Supports NAD+ levels and cellular repair
35% Ca-AKG: Detoxifies age-related ammonia buildup and restore DNA integrity
15% Trans-Resveratrol: Provides powerful antioxidant protection for overall cellular recovery
Science That Reaches Your Cells
Supports NAD+ Levels and Cellular Repair
Nicotinamide Riboside Hydrogen Malate (NRHM) is designed to:
Boosts NAD+ Level

Boosts NAD+ Level
NRHM is a stabilized, innovative form of Vitamin B3 — a natural and bioavailable precursor essential for the body's synthesis of NAD+. Constant dietary supplementation of NR has been shown to increase the NAD+ levels in middle aged to elderly people.
Ref: Conlon and Ford, Biochemical Pharmacology 2022; Martens et al., Nature Communications 2018
Supports Cellular Repair

Supports Cellular Repair
NRHM increases blood NAD+ levels significantly and is well-tolerated, supporting its potential use for mitochondrial dysfunction treatments.
Ref: Airhart et al., PLOS ONE 2017
Improves Cognitive Decline and Neuroprotecting

Improves Cognitive Decline and Neuroprotecting
Oral supplementation with NR can inhibit the accumulation of pathological hallmarks of Alzheimer's disease and improve learning and memory.
Ref:Braidy and Liu, Current Opinion in Clinical Nutrition & Metabolic Care 2020
Safety Profile in Human Trials

Safety Profile in Human Trials
NR is well tolerated in humans with limited adverse effects compared to other NAD+ precursors. It is uniquely and orally bioavailable in humans. 6 weeks of NR supplementation at 1000mg/day dose is well-tolerated in healthy middle-aged and older adults and effectively increases blood cellular NAD+ concentrations.
Ref: Trammell, S., Schmidt, M., Weidemann, B. et al. Nature 2016; Martens, C.R., Denman, B.A., Mazzo, M.R. et al., Nature 2018
Maintains Physical Strength and Cognitive Vitality
Calcium Alpha-Ketoglutarate (Ca-AKG) is designed to:
Supports Cognitive Vitality

Supports Cognitive Vitality
Ca-AKG is a stable form of AKG, a compound found naturally in the body. It plays a key role in the Krebs cycle and is vital for making amino acids, which can enhance neurotransmitter production important for cognitive function.
Ref: Naeini et al., Experimental Gerontology 2023
Increases Focus and Clear Brain Fog

Increases Focus and Clear Brain Fog
Ca-AKG has been identified as a potential neuroprotective compound for various neurological conditions. It aids in providing the necessary energy for brain cells, which may enhance mental clarity, concentration, and overall cognitive function.
Study showed that dietary intake of AKG is a feasible and promising therapeutic approach for Parkinson’s disease.
Ref: Kostiuchenko et al., BBA Advances 2022; Zhang et al., Cellular and Molecular Life Sciences 2023
Decreases Frailty

Decreases Frailty
Research indicated that Ca-AKG can enhance bone density and reduce age-related bone loss in humans.
Ref: Wang et al., Nature Communications 2020
AKG and NAD+ modulation enhances DNA Repair

AKG and NAD+ modulation enhances DNA Repair
Recent research indicates that the supplementation of AKG, when paired with NAD+ modulation, enhances the functionality of the DNA repair mechanisms.
Ref: Xiang et al., Nature 2024
Reduces Inflammation for Overall Health
Trans-Resveratrol is designed to:
Collagen Synthesis and Wrinkle Reduction

Collagen Synthesis and Wrinkle Reduction
Resveratrol enhances collagen synthesis by activating estrogen receptors, leading to wrinkle reduction.
Ref: Leis et al., 2022
Supports Cardiovascular Health

Supports Cardiovascular Health
Trans-Resveratrol may help reduce blood clotting, potentially reducing the risk of cardiovascular events.
Ref: WebMD 2019
Enhances NAD+ Levels via AMPK Activation

Enhances NAD+ Levels via AMPK Activation
Resveratrol activates AMP-activated protein kinase (AMPK), an energy sensor in cells. This activation leads to an increase in NAD⁺ levels, which in turn stimulates the activity of sirtuins, particularly SIRT1. SIRT1 is involved in various cellular processes, including mitochondrial function and energy metabolism.
Ref: Desquiret-Dumas et al., Journal of Biological Chemistry 2013
Helps Maintain Optimal Vitality

Helps Maintain Optimal Vitality
Resveratrol, a natural compound found in certain foods, has been widely studied for its potent antioxidant properties. Its activation of sirtuins may lead to reduced inflammation and oxidative stress, offering potential benefits in chronic inflammatory conditions.
Ref: Salehi et al., Biomedicines 2018
Obsessed With Quality
We focus on top-notch ingredients and the same safety standards we’d expect for our own families (since they use them too!)
Rooted In Science, Made by Heart
  | NaturNewborn NAD+ Booster | Others |
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Effective Daily Dose |
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Triple Anti-Aging Ingredients |
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3rd Party Lab Tested EVERY BATCH |
Don't Just Take Our Words
Countless individuals are turning to our products and enjoying their proven benefits
A Real Game Changer For Your Cells
Your cells feel the benefits before you do

NatureNewborn Defy Aging
Shown to
21%
Increased in energy level
41%
Improved overall skin health
84%
Increased muscle health & performance
91%
Better quality sleep
As shown in mammalian and human studies, and customer surveys